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KMID : 1094020060230020186
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Journal of Veterinary Clinics
2006 Volume.23 No. 2 p.186 ~ p.189
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Systemic Amyloidosis in a Cocker Spaniel
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Pak Son-Il
Kim Doo
Han Jeong-Hee
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Abstract
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A 7-month-old female Cocker spaniel dog was examined for chronic anemia. Based on information provided by local clinician the patient had had a ’flu-like’ illness three weeks before submission of the sample, had a fever of , and had mild hepatomegaly. This dog had also history of weight loss, vomiting, anorexia, dehydration, lethargy, ascites, polyuria and polydipsia. A blood smear showed non-regenerative anemia. Thoracic radiograph showed irregular shadowing in the left mid-zone. Serum biochemical results showed a hypercalcemia, azotemia, hypercholesterolemia, hyperphosphatemia, hypoalbuminemia, and metabolic acidosis. Results of urinalysis showed proteinuria, slightly acidic with isosthenuria. Histopathologic examination of tissue sections revealed amyloid deposits in multiple sites including kidneys, liver and spleen.
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KEYWORD
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Amyloidosis, Nephritic syndrome, Dog
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